Lionel Breton

There is increasing evidence suggesting that gut and others organs do not act as isolated organs but are involved in a straight relationship. Emerging research has shown that gut and probably skin microbiota may play a critical role at the interface of many organs. Therefore, it is not surprising that conditions affecting one organ’s microbiota may also have manifestations in the others.

More importantly, a better understanding of the intestinal microflora and its subsequent relationship with brain, skin or lung may provide new insights into developing unique product candidates that will accurately treat a spectrum of diseases indications with current unmet needs including immune training for infectious diseases' prevention. As the microbiome continues to enter the scientific mainstream, this multiple complexity organs are largely unexplored, some examples are already published on gut-brain connections in autism, Parkinson and depressive illness and a few on gut-lung in inflammatory pneumopathies. Finally, recent publications described a gut-brain-skin connection in some dermatosis and how skin could be involved in some neurodegenerative disorders in a near future.