Robotic Automation in Aseptic Filling:
- Robotic arms are VHP compatible and can be sterilized in place
- Finely tuned programming of critical motions along all axes using teach points and recipes
- Speed and repeatability – extremely precise in following the same motions every time, within ±0.05 mm
- Functional safety – integrated pre-programmed safety features monitors advanced safety conditions based on position and speed of arm
- Hands-off processing, operators simply need to set up the machine and let the robots handle the entire fill-close process
- Greatly reduced footprint – Robots allow for optimal utilization of space by allowing you to use one system for multiple processes and are not constricted to a linear process flow
Aseptic Process Development, Validation, and Evaluation:
- Robots offer extreme repeatability and precision in process
- Programmable recipes and slowed down step-through motions allow for fine-tuning the most minute details of your process and test runs as needed
- Electronic batch records can be exported for highly detailed data and analysis
- Environmental monitoring can be used confirm aseptic environment, along with temperature and pressure management within integrated isolated barrier systems
- Training automated robots to follow a process will always be more reliable than training a team of human operators and trusting them to follow a process
Considerations for multi-product facilities:
- High yield and high potency products
- Minimizing product loss and overall risk to products and operators
- Flexible format machines allows for rapid changeovers, a single machine can process a variety of products in a variety of container formats
- Scalability of operations as drug development moves from research to commercial production
- Programmable recipes allow for simplicity in preparing machine for different products
